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杨俊杰

2022年07月12日 02:23  点击:[]

杨俊杰,教授,硕士生导师。主要从事与精准诊疗相关的免疫、生物医学及人体微生物组学研究。

主要学习经历

山东师范大学,发育生物学专业,博士。

National University of Singapore, Yong Loo Lin School of Medicine,Department of Microbiology & Immunology,山东省公派高级访问学者。

主要研究方向

生物医学免疫/微生物组与肿瘤发生,重点研究免疫及微生物组参与疾病发生发展的潜在机制;多组学网络关联和拓扑特征分析等。

主要科研成果

主持山东省自然科学基金项目1项,参与山东省重点研发计划项目1项及山东省重大科技创新工程项目1项。授权国家发明专利3项,国家新型实用专利5项,计算机软件著作权1项。出版学术专著1部。近五年发表SCI学术论文21篇。

代表性论文发表在mSystems, 2020(Q1,IF : 7. 342),Pharmacological Research, 2020 (Q1, IF : 10.334),Genomics,Proteomics & Bioinformatics,2019 (Q1, IF : 9.5),Frontiers in Microbiology,2019 (Q1, IF : 6.064),Frontiers in Oncology,2018 (Q2, IF : 5.738),Microbiome, 2018 (Q1, IF : 15.5)等。

1) Changying Zhao#, Zefeng Wei#,Junjie Yang#, Jiaming Zhang, Chunna Yu, Aijun Yang, Min Zhang, Lin Zhang, Ye Wang, Xiaofeng Mu, Xueyuan Heng, Huijun Yang, Zhongtao Gai, Xuenan Wang, Lei Zhang*. Characterization of vaginal microbiome in women with infertility and its potential correlation with hormone stimulation during IVF surgery.mSystems, 2020, 5(4): e00450-20.

2)Ying Wang#, Ning Li#,Jun-Jie Yang#, Dong-Mei Zhao, Bin Chen5, Guo-Qing Zhang, Shuo Chen, Rui-Fang Cao, Han Yu, Chang-Ying Zhao, Lu Zhao, Yong-Sheng Ge, Yi Liu, Le-Hai Zhang, Wei Hu, Lei Zhang*, Zhong-Tao Gai*.Probiotics and fructo-oligosaccharide intervention modulate the microbiota-gut brain axis to improve autism spectrum reducing also the hyper-serotonergic state and the dopamine metabolism disorder.Pharmacological Research, 2020, 157:104784.

3)Junjie Yang#, Jiaming Zhang#, Changying Zhao#, Zhongtao Gai, Xiaofeng Mu, Ye Wang, Chunling Zhang, Zhenzhen Su, Lihe Gao, Dequan Zhu, Zhiwen Zuo, Xueyuan Heng*, Lei Zhang*. Blood loss leads to increase in relative abundance of opportunistic pathogens in the gut microbiome of rabbits.Current Microbiology, 2020, 77: 415-424.

4)Li Ning#,Junjie Yang#, Jiaming Zhang, Cheng Liang, Ying Wang, Bin Chen, Changying Zhao, Jingwen Wang, Guangye Zhang, Dongmei Zhao, Yi Liu, Lehai Zhang, Jun Yang, Guimei Li*, Zhongtao Gai*, Lei Zhang*, Guoping Zhao. Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment.Genomics, Proteomics & Bioinformatics, 2019, 17(1):26-28.

5)Zhen Zhang#,Junjie Yang#, Qiang Feng, Bin Chen3, Meihui Li,Cheng Liang, Mingyu Li, Zhihui Li, Qin Xu, Lei Zhang*, Wantao Chen*.Compositional and Functional Analysis of the Microbiome in Tissue and Saliva of Oral Squamous Cell Carcinoma.Frontiers in Microbiology, 2019, 10: 1439.

6) Fanghua Zhang#, Meng Wang#,Junjie Yang#, Qian Xu, Cheng Liang, Bin Chen, Jiaming Zhang, Ying Yang, Huiling Wang, Yongfang Shang, Ye Wang, Xiaofeng Mu, Dequan Zhu, Chunling Zhang, Minxiu Yao*, Lei Zhang*. Response of gut microbiota in type 2 diabetes to hypoglycemic agents.Endocrine, 2019, 66(3):485-493.

7) Meng Wang#,Junjie Yang#, Zhongtao Gai, Shengnan Huo, Jianhua Zhu, Jun Li, Ranran Wang, Sheng Xing, Guosheng Shi, Feng Shi*, Lei Zhang*. Comparison between digital PCR and real-time PCR in detection of Salmonella typhimurium in milk.International Journal of Food Microbiology, 2018, 266: 251-256.

8)XueYing Zhang#, Gansukh Sukhchuluun#, TingBei Bo#, QingSheng Chi,JunJie Yang, Bin Chen, Lei Zhang*,DeHua Wang*, Huddling remodels gut microbiota to reduce energy requirements in a small mammal species during cold exposure,Microbiome, 2018, 6: 103.

9)Junjie Yang#, Xiaofeng Mu, Ye Wang, Dequan Zhu, Jiaming Zhang, Cheng Liang, Bin Chen, Jingwen Wang,Changying Zhao, Zhiwen Zuo, Xueyuan Heng*, Chunling Zhang*, Lei Zhang*. Dysbiosis of the salivary microbiome is associated with non-smoking female lung cancer and correlated with immunocytochemistry markers.Frontiers in Oncology, 2018, 8: 520.

10)Shen Meng#, Bin Chen#,Junjie Yang#,Jingwen Wang, Dequan Zhu, Qingsong Meng*, Lei Zhang*. Study of Microbiomes in Aseptically Collected Samples of Human Breast Tissue Using Needle Biopsy and the Potential Role of in situ Tissue Microbiomes for Promoting Malignancy.Frontiers in Oncology, 2018, 8:318.